Using of supersaturated oxygen delivery (SSO2 therapy) in patients with acute myocardial ischemia

Oxygen is the main participant in redox reactions body and its deficiency can lead to organ dysfunction. Thus, a decrease blood flow certain region of myocardium patients with coronary heart disease cause attack. According experimental studies, early reperfusion reduces infarct size, clinical studies have shown that effective affected artery prevention re-occlusion basis for minimizing size mortality. Timely performed percutaneous intervention acute myocardial infarction significantly reduced mortality rate risk failure. Despite endovascular treatment effectiveness, there still need additional methods cardioprotection, reducing area preventing development failure adverse left ventricular remodeling. Blood oxygen supersaturation (SSO 2 therapy) one adjuvant cardioprotection ischemia. This review describes possible mechanisms implementing cardioprotective effects SSO2 therapy, technology equipment necessary application this technique. In addition, results on SSO therapy are consecrated. Of note, only multicentre prospective randomized controlled trial uniform randomization was performed. use limited by commercial equipment.